As always, talks will be the fourth Tuesday of the month at 7pm, upstairs in the Community Room at the Pittsford Plaza Barnes and Noble, 3349 Monroe Ave. All talks are free, and coffee and cookies are provided.
This Fall, our lineup will be
September 24
September 24
“Health around the clock: human circadian rhythm in health and disease”
Dr. Brian J. Altmann, Ph.D.
Assistant Professor, Department of Biomedical Genetics
University of Rochester Medical Center
Dr. Brian J. Altmann, Ph.D.
Assistant Professor, Department of Biomedical Genetics
University of Rochester Medical Center
Circadian rhythms in mammals are 24-hour cycles that govern gene regulation and cellular metabolism. While many cancers have altered or disrupted circadian rhythms, there is little understanding of the implications of this disruption on cancer cell metabolism, tumor cell growth, and prognosis. We have previously shown that the MYC oncogene, commonly overexpressed in many human cancers, disrupts circadian rhythm and metabolic oscillations, which may provide a growth advantage to the cancer cell.https://www.urmc.rochester.edu/labs/altman.aspx
Our research focuses on identifying the intersections between circadian rhythm, cancer cell physiology, and metabolism. We utilize diverse cell line models of cancer and mouse MYC-driven lung cancer to focus on amplified MYC, the extended MYC family of related proteins, and nutrient input and metabolic stress signaling in circadian rhythm control. Better understanding of how tumors and metabolic input modulate the clock and the circadian metabolic cycle could aid in developing novel treatment strategies to time increased efficacy and reduced toxicity.
October 22
“Bacterial seashells: How to build your environment using bacteria” Dr. Anne Meyer, Ph.D.
Assistant Professor, Department of Biology
University of Rochester
November 26
“Perception as controlled hallucination”
Dr. Edmund Lalor, Ph.D.
Associate Professor, Departments of Biomedical Engineering and Neuroscience
University of Rochester
Dr. Edmund Lalor, Ph.D.
Associate Professor, Departments of Biomedical Engineering and Neuroscience
University of Rochester